Ketorolac Contraindications and Precautions

Contraindications and High-Risk Populations

• The American Academy of Family Physicians recommends avoiding ketorolac in patients with aspirin/NSAID-induced asthma, pregnancy, and cerebrovascular hemorrhage 1
• The National Comprehensive Cancer Network guidelines identify high-risk populations requiring dose reduction or avoidance, including age ≥60 years with cardiovascular disease risk, history of peptic ulcer disease, concurrent anticoagulant use, and compromised fluid status 2, 3, 4, 5