Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 11/21/2025

Lithium Toxicity Symptoms and Diagnosis

Clinical Presentation

  • Lithium toxicity can present as drug-induced neurological dysfunction that mimics stroke, particularly with confusion, ataxia, and altered consciousness, highlighting the importance of obtaining medication history and lithium levels in patients presenting with acute neurological changes, as recommended by the American Heart Association, based on evidence from the Stroke journal 1