Dosing of Vildagliptina in Advanced Renal Insufficiency

Comparison with Other DPP-4 Inhibitors

The American Journal of Kidney Diseases notes that most DPP-4 inhibitors require dose adjustments in advanced renal insufficiency, including sitagliptina, saxagliptina, and alogliptina 1, 2
The American Journal of Kidney Diseases also states that linagliptina, similar to vildagliptina, does not require additional dose adjustments in patients with impaired renal function 1, 2
The American Journal of Kidney Diseases recommends that DPP-4 inhibitors, including vildagliptina, are suitable options for patients with chronic kidney disease due to their low risk of hypoglycemia 2