Febuxostat Pharmacokinetics and Clinical Implications

Comparison with Other Medications

• Febuxostat has a half-life similar to short-acting NSAIDs like ibuprofen (2-6 hours) 1
• Febuxostat's half-life is considerably shorter than anticoagulants such as dabigatran (14-17 hours) 2, 3
• Febuxostat's half-life is shorter than anticoagulants such as rivaroxaban (5-13 hours) and apixaban (12 hours) 4, 5