Common Peroneal Nerve Block Adverse Effects

Anatomical Considerations

The common peroneal nerve is located just medial to the biceps femoris tendon and near the fibular head, making it susceptible to compression, according to the American College of Radiology 1
Pressure near the fibular head from contact with a hard surface or rigid support significantly increases the risk of peroneal neuropathy, as reported by the American Society of Anesthesiologists 3, 4

Prolonged pressure on the peroneal nerve at both hip and knee joints can increase risk, and specific padding to prevent contact of the peroneal nerve with hard surfaces may decrease the risk of peroneal neuropathy, as recommended by the American Society of Anesthesiologists 4, 5
Care or avoidance of the fibular head region is recommended when performing procedures near this area, according to the American College of Radiology 1
Inappropriate use of padding (e.g., padding too tight) may paradoxically increase the risk of neuropathy, as noted by the American Society of Anesthesiologists 5

When planning procedures near the common peroneal nerve, care should be taken to avoid compression at the fibular head, according to the American College of Radiology 1
Thorough testing for block success is encouraged to prevent complications, as suggested by the journal Anaesthesia 6