CDC‑Recommended First‑Line Treatment and Contraindications for Mycoplasma genitalium in Pregnancy

First‑Line Antimicrobial Therapy

Contraindicated Antimicrobials

Patient Counseling and Behavioral Recommendations

Treatment of Mycoplasma genitalium in Pregnancy

Evidence Base and Treatment Approach

• The Centers for Disease Control and Prevention recommends azithromycin 1 g orally in a single dose as safe and effective for chlamydial infections in pregnancy, which aligns with its use for Mycoplasma genitalium infection 3
• Doxycycline is contraindicated in pregnant women, according to the Centers for Disease Control and Prevention 3