Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/24/2025

Adult Cardiopulmonary Resuscitation Guidelines

Basic Life Support

  • The American Heart Association recommends that all rescuers should provide chest compressions for victims of cardiac arrest, with a compression depth of 5-6 cm at a rate of 100-120 compressions per minute, allowing for complete chest recoil between compressions 1, 2, 3
  • Check for responsiveness by shouting and tapping the victim, and if unresponsive, activate emergency response system and get an AED (or send someone to do so) 4, 5
  • Look for no breathing or only gasping and check pulse simultaneously (within 10 seconds) 6
  • Begin CPR immediately with chest compressions if no pulse is detected within 10 seconds, and perform cycles of 30 compressions followed by 2 breaths 4, 7, 8
  • Use the AED as soon as it becomes available 9
  • Untrained rescuers should provide compression-only CPR, while trained rescuers may provide ventilation (rescue breaths) in addition to compressions 1, 10
  • After identifying cardiac arrest, a lone responder should activate emergency response system first, then begin CPR 2

Advanced Life Support

  • Check rhythm every 2 minutes, and for shockable rhythms (VF/pVT), deliver shock immediately and resume CPR for 2 minutes before reassessing rhythm 5
  • Establish IV/IO access, and administer epinephrine every 3-5 minutes, considering amiodarone or lidocaine for refractory VF/pVT 5, 7

Special Considerations

  • For victims with a pulse but no normal breathing, provide rescue breathing at a rate of 1 breath every 6 seconds (10 breaths/minute), and check pulse every 2 minutes 6
  • For suspected opioid overdose, administer naloxone if available 6

Common Pitfalls and Caveats

  • Healthcare providers often take too long to check for a pulse, leading to delays in starting compressions, and minimizing pauses in chest compressions is critical for survival 10
  • Incomplete chest recoil prevents full cardiac refilling, and allowing complete chest recoil between compressions is essential 7

REFERENCES