Cefepime Dosing and Safety in Pediatric Patients
Dosing Guidelines
- For complicated intra-abdominal infections, the recommended dose is 100 mg/kg/day administered every 12 hours, as suggested by the Infectious Diseases Society of America 1, 2
- For empiric therapy in culture-negative endocarditis with prosthetic valve, the American Heart Association recommends 150 mg/kg/day IV in 3 equally divided doses for 6 weeks 3, 4, 5
- For treatment of gram-negative enteric bacilli infections, a dose of 100-150 mg/kg/day IV divided every 8 hours up to 2-4 g daily is recommended 6