Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/3/2025

Antipsychotic-Induced Weight Gain

Critical Clinical Considerations

  • Weight gain with atypical antipsychotics may be extreme and represents the most common significant problem associated with their use, with the American Academy of Child and Adolescent Psychiatry guidelines emphasizing particular concern in pediatric populations 1, 2
  • The American Academy of Child and Adolescent Psychiatry guidelines highlight that weight gain with atypical antipsychotics is a significant problem, especially in children 1