Clonidine Transdermal Patch Administration and Monitoring

Monitoring and Precautions

• The American College of Cardiology recommends monitoring for common side effects including orthostatic hypotension, drowsiness, dry mouth, and sedation 1
• The American College of Cardiology advises against abrupt discontinuation of clonidine, which may induce hypertensive crisis; clonidine must be tapered to avoid rebound hypertension 1
• The American College of Cardiology notes that clonidine is generally reserved as a last-line agent due to significant CNS adverse effects, especially in older adults 1