Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Article ID: 27a35385-0a43-4ff2-b7af-b638fc1f0de7

Updated: 9/28/2025

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/28/2025

Nifedipine Protocol for Tocolysis in Preterm Labor

Safety Considerations

The American Heart Association recommends avoiding the combination of nifedipine with magnesium sulfate due to the risk of precipitous blood pressure drop 1

Clinical Indications and Contraindications

The American College of Cardiology advises against the use of immediate-release nifedipine in patients with cardiovascular disease without concomitant beta-blockade 2, 3

REFERENCES

1

seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure. [LINK]

Hypertension, 2003

2

2014 aha/acc guideline for the management of patients with non-st-elevation acute coronary syndromes: a report of the american college of cardiology/american heart association task force on practice guidelines. [LINK]

Circulation, 2014

3

2014 aha/acc guideline for the management of patients with non-st-elevation acute coronary syndromes: executive summary: a report of the american college of cardiology/american heart association task force on practice guidelines. [LINK]

Circulation, 2014

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