Concomitant Administration of Prevnar and Shingrix

Administration Guidelines

• The Centers for Disease Control and Prevention recommends administering both Prevnar and Shingrix vaccines at separate anatomic sites during the same visit, using different limbs when possible to minimize local injection site reactions 1, 2, 3
• The guideline advises against mixing vaccines in the same syringe 4
• Full recommended doses of each vaccine should be administered 5

Important Considerations About Adjuvants

• The Advisory Committee on Immunization Practices acknowledges limited data on simultaneous administration of multiple non-aluminum adjuvant-containing vaccines, but notes that vaccination should not be delayed if a specific product is not available 1, 2, 3

Clinical Benefits of Concomitant Administration

• Simultaneous administration of Prevnar and Shingrix increases the probability that patients will be fully immunized, preventing missed vaccination opportunities, particularly for patients unlikely to return for future visits 4, 5
• Concomitant administration ensures age-appropriate vaccination completion and reduces the number of clinic visits required 4, 5

Common Pitfalls to Avoid

• The Centers for Disease Control and Prevention advises against delaying either vaccine unnecessarily, as evidence supports same-visit administration 1, 3
• It is essential to ensure proper documentation of both vaccines, including anatomic sites recorded 5