Topical Tranexamic Acid for Hyperpigmentation Treatment

Comparative Efficacy and Treatment Protocols

• Intradermal TXA injections (4 mg/mL) provide an alternative to topical TXA, though intradermal PRP injections demonstrate superior efficacy compared to intradermal TXA, as noted by the Periodontology 2000 guidelines 1
• Combining topical 3% TXA serum with strict broad-spectrum sunscreen (SPF 50+) reapplied every 2-3 hours during sun exposure is recommended, according to Praxis Medical Insights 2, 3