Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/29/2025

Airway Management in Cardiac Arrest

Key Considerations

  • The American Heart Association recommends that skilled providers with frequent experience or regular retraining can perform endotracheal intubation safely during cardiac arrest (Class I, LOE B) 1
  • Inexperienced providers attempting intubation produce unacceptably high complication rates, including prolonged interruptions in chest compressions, unrecognized esophageal intubation, tube displacement, and hypoxemia from prolonged attempts 1, 3
  • The American Heart Association suggests that EMS systems performing prehospital intubation must provide ongoing quality improvement programs to minimize complications (Class IIa, LOE B) 1

Chest Compression Interruptions

  • Interruptions in chest compressions must be limited to less than 10 seconds for laryngoscopy and tube passage through the vocal cords 1, 4
  • The intubating provider must be fully prepared with the laryngoscope blade and tube ready before compressions are paused 1
  • Chest compressions should resume immediately after the tube passes through the vocal cords 1

Alternative Airway Strategies

  • The American Heart Association recommends that either bag-mask device or advanced airway may be used for oxygenation and ventilation during CPR in both in-hospital and out-of-hospital settings (Class IIb, LOE C-LD) 2
  • Supraglottic airway devices or endotracheal tubes may be used as the initial advanced airway during CPR (Class IIb, LOE C-LD) 2
  • The laryngeal mask airway is an acceptable alternative to bag-mask ventilation (Class IIa, LOE B) or endotracheal intubation (Class IIa, LOE C) for healthcare professionals trained in its use 1, 3

Ventilation Strategy

  • Deliver 10 breaths per minute with continuous compressions once advanced airway is placed 7
  • Avoid hyperventilation, which compromises venous return and causes hypotension 8
  • Target normocapnia (PaCO2 35-40 mmHg) 8, 6

Special Populations

  • Conventional CPR with ventilations and compressions is superior to compression-only CPR for pediatric asphyxial arrest 11
  • Bag-mask ventilation with manual airway maneuvers is recommended for short periods in out-of-hospital settings 11
  • Supraglottic airways may be helpful when bag-mask ventilation is ineffective 11