Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/7/2025

Ashwagandha-Induced Liver Injury

Key Characteristics

  • Fatty liver disease (NAFLD) is a chronic metabolic condition characterized by hepatic steatosis, affecting 20-30% of the general population, as noted by the American Gastroenterological Association 1, 2

Clinical Presentation and Management

  • The American Association for the Study of Liver Diseases recommends that patients with NAFLD focus on weight loss, Mediterranean diet, and metabolic risk factor control for management 3, 4, 5
  • The European Society for Clinical Nutrition and Metabolism notes that malnutrition can cause fatty liver, but it is fully reversible with refeeding and does not cause chronic liver disease 6, 7