Impact of Supplements on Blood Pressure

Supplements Known to Increase Blood Pressure

Herbal supplements are categorized as having "high" potential to increase blood pressure according to clinical guidelines from the American Academy of Pediatrics 1, 2
Yohimbine (found in some formulations of tongkat ali) is specifically identified as a substance that can increase blood pressure, as reported by the American Heart Association 4

Ashwagandha, fenugreek, maca root, artichoke extract, and nettle root are not specifically mentioned in major hypertension guidelines as substances that increase blood pressure, according to the American College of Cardiology and the American Heart Association 3, 5, 4
Boron is not listed among substances that increase blood pressure in clinical guidelines from the American Academy of Pediatrics and the American Heart Association 1, 2, 3

Pre-existing hypertension increases susceptibility to blood pressure changes from supplements, as noted by the American Heart Association 4
Concurrent use of multiple substances with cardiovascular effects can potentiate blood pressure changes, according to the American Heart Association 4

Screen all patients for use of supplements that may increase blood pressure or interfere with antihypertensive medications, as recommended by the American Heart Association 4
Monitor blood pressure when starting any new supplement, especially in patients with pre-existing hypertension or cardiovascular risk factors, as advised by the American Heart Association 4
Consider discontinuation of supplements if blood pressure increases significantly after initiation, according to the American Heart Association 4
Exercise caution with supplements marketed for athletic performance or sexual enhancement, as these often contain stimulants or other ingredients that may affect blood pressure, as warned by the American Academy of Pediatrics 1, 2

Individual responses to supplements may vary based on genetics, existing medical conditions, and concurrent medications, as noted by the American Heart Association 4