Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/20/2025

Augmentin Dosage Guidelines for Adolescents

Dosage Recommendations

  • The American Academy of Pediatrics and Infectious Diseases Society of America recommend a dose of 875 mg amoxicillin component every 12 hours for skin/skin structure or respiratory tract infections, which corresponds to the standard Augmentin formulation of 875 mg amoxicillin/125 mg clavulanate 1

Treatment Duration

  • The American Academy of Family Physicians recommends a minimum 10-day treatment course for Streptococcus pyogenes infections to prevent acute rheumatic fever 2

Maximum Dosage

  • The maximum daily dose of amoxicillin for both adults and children is 4 grams per day, and for children, high-dose amoxicillin is defined as 90 mg/kg/day, not to exceed 4000 mg/day 3

REFERENCES

3

Maximum Dose of Amoxicillin [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025