Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/4/2025

Acute Migraine Treatment in Children

First-Line Treatment Options

  • The American Academy of Neurology recommends ibuprofen as first-line medication for acute migraine treatment in children at a dose appropriate for body weight 1, 2
  • For adolescents aged 12-17 years, multiple NSAIDs and triptans have been approved for acute migraine treatment by the American Academy of Neurology 1, 2

Alternative Treatment Options

  • Nasal spray formulations of sumatriptan and zolmitriptan may be more effective in adolescents, according to the American Headache Society 2