Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/9/2025

Imaging Guidelines for Left Lower Rib and Upper Left Abdominal Pain

Rationale for CT Abdomen and Pelvis with IV Contrast

  • The American College of Radiology recommends CT abdomen and pelvis with IV contrast as the initial imaging for patients with acute abdominal pain, providing a comprehensive evaluation of abdominal and thoracic structures, with high sensitivity and specificity (up to 98% accuracy) for diagnosing various causes of left-sided abdominal and lower chest pain 1, 2
  • IV contrast improves the characterization and detection of subtle bowel wall abnormalities and complications such as abscesses, according to the American College of Radiology 2
  • CT can identify alternative diagnoses that may present with similar clinical symptoms, avoiding misdiagnosis, as suggested by the American College of Radiology 2

Potential Diagnoses to Consider

  • Diverticulitis is a common cause of left lower quadrant pain that may radiate to the left lower rib area, according to the American College of Radiology 1, 2
  • Diaphragmatic hernia can present with pain in the lower chest or upper abdomen, as reported by the World Journal of Emergency Surgery 3, 4
  • Visceral pathology (splenic, gastric, pancreatic, or colonic issues) should be considered as a potential cause of left-sided abdominal pain, according to the American College of Radiology 1

Advantages of CT Over Other Imaging Modalities

  • Ultrasound may be useful for specific conditions but has limited value as the initial imaging for non-gynecologic left-sided abdominal pain, as stated by the American College of Radiology 1
  • MRI is not recommended for initial evaluation of acute abdominal pain due to its limited sensitivity for extraluminal air and calculi, time-consuming nature, requirement for metal screening, and susceptibility to motion artifacts, according to the American College of Radiology 1

Technical Considerations

  • Low-dose CT techniques can achieve radiation dose reduction of 75-90% compared to standard-dose CT while maintaining similar sensitivity and specificity, as reported by the American College of Radiology 2
  • Administration of oral or colonic contrast may be helpful for bowel luminal visualization in addition to IV contrast, as suggested by the American Academy of Family Physicians 5

Special Considerations

  • If there is concern for diaphragmatic hernia, CT scan with contrast enhancement of the chest and abdomen is strongly recommended (1B evidence), according to the World Journal of Emergency Surgery 3
  • For female patients of childbearing age, consider pelvic ultrasound first if gynecologic pathology is suspected, as recommended by the American College of Radiology 1, 2
  • In patients with renal insufficiency, CT without IV contrast may be considered, though this is less optimal, as stated by the American College of Radiology 6, 7

Potential Pitfalls to Avoid

  • Relying solely on clinical assessment for diagnosis of abdominal pain can lead to misdiagnosis rates of 34-68%, according to the American College of Radiology 1
  • Overlooking diaphragmatic injuries, which can be missed on plain radiographs in up to 62% of cases, as reported by the World Journal of Emergency Surgery 3