Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/10/2025

Peritonitis in Peritoneal Dialysis: Cited Facts and Guidelines

Introduction to Peritonitis Management

  • The American Journal of Kidney Diseases recommends avoiding aminoglucósidos in patients with residual renal function due to their potential nephrotoxicity 2, 3
  • The American Journal of Kidney Diseases suggests preserving residual renal function is crucial for outcomes in peritoneal dialysis patients 2, 3

Clinical Presentation

  • The presence of cloudy dialysate is a cardinal sign of peritonitis in peritoneal dialysis patients 2
  • Abdominal pain is a common symptom of peritonitis in peritoneal dialysis patients 1
  • Fever may be present in some cases of peritonitis in peritoneal dialysis patients, but can also be absent 3

Treatment of Peritonitis

  • Praxis Medical Insights recommends a standard treatment duration of 2-3 weeks for peritonitis in peritoneal dialysis patients 1
  • The American Journal of Kidney Diseases suggests that the use of aminoglucósidos should be avoided when possible without compromising antibacterial efficacy due to their potential nephrotoxicity 2, 3

Fungal Peritonitis Treatment

  • Praxis Medical Insights recommends catheter removal as almost always necessary for successful treatment of fungal peritonitis in peritoneal dialysis patients 1
  • Systemic treatment with amphotericin B or fluconazol is recommended for fungal peritonitis in peritoneal dialysis patients 1
  • Praxis Medical Insights advises against the use of intraperitoneal amphotericin B due to the risk of chemical peritonitis 1
  • Praxis Medical Insights recommends waiting at least 2 weeks after catheter removal before placing a new catheter in patients with fungal peritonitis 1
  • Treatment duration for fungal peritonitis should be guided by clinical response, typically 2-3 weeks 1

REFERENCES

3

Peritonitis Asociada a Catéter de Diálisis Peritoneal: Tratamiento y Manejo [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025