Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/30/2025

Arachnoid Cyst Characteristics and Diagnosis

Imaging Characteristics

  • Arachnoid cysts are thin-walled sacs filled with clear CSF fluid that is isodense with normal CSF on imaging studies 1
  • On MRI, these cysts appear isointense to CSF on all sequences, with no enhancement after gadolinium administration 2
  • The MRI protocol for diagnosis should include standard T1- and T2-weighted sequences 1
  • Fluid-attenuated inversion recovery sequences are also recommended for diagnosis 2
  • Arachnoid cysts may exhibit mass effect on adjacent brain tissue 2

Location and Size

  • "Giant" cysts (>50mm in diameter) are occasionally found in the Sylvian fissure, which includes the opercular region 2