Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/31/2025

Geographic Distribution and Diagnosis of Plasmodium malariae

Global Context and Diagnostic Challenges

  • The Centers for Disease Control and Prevention recommends contacting the CDC Malaria Hotline for detailed epidemiological data specific to a location of interest, providing current incidence rates and transmission patterns for specific geographic areas 1
  • Plasmodium malariae occurs worldwide in tropical and subtropical regions where malaria is endemic, including Central and South America, sub-Saharan Africa, the Indian Subcontinent, Southeast Asia, the Middle East, and Oceania 1, 2
  • The World Health Organization recognizes P. malariae as one of four human malaria parasites alongside P. falciparum, P. vivax, and P. ovale 2, 3