Diagnostic Evaluation of Retiform Purpura

Laboratory Tests and Diagnostic Procedures

• A complete blood count with peripheral smear examination, renal and liver function tests, and specific tests based on clinical suspicion such as antiphospholipid antibodies and antinuclear antibodies are essential for diagnosis, as recommended by the American Society of Hematology 1
• Skin biopsy is a crucial diagnostic procedure, with punch biopsy from the edge of a lesion including normal-appearing skin, and request for both H&E and direct immunofluorescence studies, according to the College of American Pathologists 1