Vyvanse Treatment Guidelines for ADHD

Initial Assessment and Dosing

The American Academy of Child and Adolescent Psychiatry recommends a cardiac evaluation, including a detailed personal and family history of sudden death, ventricular arrhythmia, or structural heart disease, before initiating Vyvanse treatment 2
The American Academy of Child and Adolescent Psychiatry suggests documenting baseline height and weight before starting Vyvanse, with ongoing growth monitoring 2
The Praxis Medical Insights guideline recommends starting Vyvanse at 30 mg once daily in the morning, with a maximum dose of 70 mg daily 1

The American Academy of Child and Adolescent Psychiatry states that Vyvanse is absolutely contraindicated in patients with active psychotic disorder 2
The Praxis Medical Insights guideline notes that Vyvanse is contraindicated in patients with known hypersensitivity to amphetamine products 3

The Praxis Medical Insights guideline recommends increasing the Vyvanse dose by 10 mg or 20 mg increments at approximately weekly intervals, with a maximum dose of 70 mg daily 3
The American Academy of Child and Adolescent Psychiatry suggests monitoring vital signs, including blood pressure and pulse, at every visit 2
The Praxis Medical Insights guideline recommends using standardized ADHD rating scales to assess symptom response before each dose increase 1

The Praxis Medical Insights guideline notes that acidifying agents, such as ascorbic acid, may decrease amphetamine levels, potentially requiring a higher Vyvanse dose 5
The Praxis Medical Insights guideline suggests that if the maximum dose of 70 mg daily does not provide adequate symptom control, consideration should be given to switching to an alternative stimulant or non-stimulant medication 3