Safety of Fluoxetine in Patients with Hepatitis C

Drug Interactions and Guidelines

• The European Association for the Study of the Liver (EASL) guidelines highlight numerous potential drug-drug interactions with hepatitis C medications, particularly those metabolized through CYP3A4 1, 2
• The EASL guidelines do not list specific contraindications for fluoxetine in hepatitis C treatment, but recommend careful assessment of potential drug interactions 1, 2, 3, 4