Magnesium and Thiamine Relationship

Clinical Implications

• The Academy of Nutrition and Dietetics recommends correcting concomitant magnesium deficiency when treating thiamine deficiency, as magnesium is necessary for adequate function of thiamine-dependent enzymes 1
• Critically ill patients have increased metabolic demands, making them a high-risk population for combined magnesium and thiamine deficiency 2

Practical Management

• When treating suspected or confirmed thiamine deficiency, always assess and correct magnesium status concurrently, as recommended by the Academy of Nutrition and Dietetics 1