Ofloxacin Dosing Recommendations for Specific Infections

Infection-Specific Dosing

• For nongonococcal urethritis, the Centers for Disease Control and Prevention (CDC) recommends 300 mg orally twice daily for 7 days 1

Pelvic Inflammatory Disease

• For acute pelvic inflammatory disease, the CDC recommends 400 mg orally twice daily for 14 days, and for parenteral treatment, 400 mg IV every 12 hours, typically with metronidazole 500 mg IV every 8 hours 2, 3

Common Pitfalls and Caveats

• When treating PID, the CDC notes that ofloxacin lacks adequate anaerobic coverage, and considers adding metronidazole for complete coverage 3, 4