Long-Acting Injectable Antipsychotics

Introduction to LAI Antipsychotics

• The currently available LAI antipsychotics include both first-generation agents and second-generation agents, with second-generation LAIs being preferred due to better tolerability and fewer neurological side effects, as recommended by the American College of Psychiatry 1

First-Generation LAI Antipsychotics

• Fluphenazine decanoate is available as a first-generation depot formulation, according to the British Journal of Psychiatry guidelines 2

Second-Generation LAI Antipsychotics

• No cited facts are available for second-generation LAI antipsychotics that meet the inclusion criteria.