Tolterodine Treatment for Overactive Bladder

Efficacy

• The European Urology guidelines suggest that tolterodine demonstrates significant improvements in overactive bladder symptoms compared to placebo, with clinical benefits including reduction in micturition frequency and decrease in urge incontinence episodes 1

Special Considerations

• The European Association of Urology recommends that before initiating antimuscarinic therapy like tolterodine, it's critical to check post-void residual volume in patients with suspected bladder outlet obstruction to avoid overflow incontinence, and in men with lower urinary tract symptoms and overactive bladder, tolterodine may be used in combination with alpha-blockers for improved symptom control 3
• According to clinical guidelines, failure to distinguish between different types of incontinence can lead to inappropriate medication selection, and tolterodine may be used in combination with alpha-blockers for improved symptom control 2