Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/31/2025

Diagnosis and Management of Superficial Subcutaneous Soft Tissue Masses

Diagnostic Approach

  • The American College of Chest Physicians guidelines suggest that MRI should be obtained if ultrasound findings are indeterminate 5
  • For lesions with atypical features, such as irregular margins, solid components, vascularity, or deep extension, MRI and biopsy are recommended before surgical intervention 4

Management Algorithm

  • If a simple cyst appearance is confirmed on ultrasound, reassurance is appropriate, with excision only if symptomatic 1