Management of Group B Streptococcus in Urine Culture

Assessment and Treatment Approach

The Centers for Disease Control and Prevention recommends that GBS in urine at concentrations ≥10^4 colony-forming units/ml should be reported by laboratories whether in pure culture or mixed with a second microorganism 1, 2
The presence of GBS in urine at this concentration represents a clinically significant finding that requires treatment, according to the Centers for Disease Control and Prevention 3
Failing to treat GBS bacteriuria at concentrations ≥10^4 CFU/ml represents a clinically significant finding that requires treatment, as stated by the Centers for Disease Control and Prevention 1, 2

For patients with penicillin allergy, antibiotic susceptibility testing should be performed to guide alternative therapy, as recommended by the Centers for Disease Control and Prevention 4

Extended therapy may be considered if symptoms are severe or if there are complicating factors, according to the Centers for Disease Control and Prevention 2