Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/14/2025

Dilation and Curettage Procedure-Related Complications and Diagnostic Accuracy

Pre-Procedure and Intraoperative Considerations

  • Endoscopists performing fewer than 500 procedures are four times more likely to cause uterine perforation, highlighting the importance of experience in minimizing complications 1, 2

Post-Procedure Assessment and Complications

  • The National Comprehensive Cancer Network recommends inspecting curetted material for completeness and sending it for histopathologic examination to ensure accurate diagnosis 3
  • Estimating blood loss is crucial during and immediately after the procedure to monitor for excessive bleeding 4
  • Post-procedure infection, characterized by fever and pelvic pain, can occur, especially with retained products and prolonged procedure time, emphasizing the need for careful patient monitoring 1, 4
  • Excessive bleeding, defined as soaking through more than one pad per hour for 2 consecutive hours, requires immediate evaluation and intervention 1, 4

Special Considerations for Diagnostic Accuracy

  • For fertility-sparing evaluation in young women with grade 1 endometrial cancer or atypical hyperplasia, D&C with or without hysteroscopy is required for definitive histologic diagnosis, as recommended by the European Society for Medical Oncology and the National Comprehensive Cancer Network 5, 3, 2
  • D&C is superior to office biopsy for accurate tumor grading, despite office methods having high sensitivity for detecting carcinoma, according to the American College of Obstetricians and Gynecologists 2
  • Office biopsy has a 10% false-negative rate, and a negative result in symptomatic patients requires fractional D&C under anesthesia to ensure accurate diagnosis 1, 2
  • Hysteroscopy can be used as an adjunct to evaluate focal lesions like polyps in patients with persistent undiagnosed bleeding, as suggested by the American Association of Gynecologic Laparoscopists 1

REFERENCES

1

Risks and Complications of Dilation and Curettage [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

2

Indications for Dilation and Curettage Based on Ultrasound Findings [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

3

uterine neoplasms, version 1.2014. [LINK]

Journal of the National Comprehensive Cancer Network : JNCCN, 2014

4

Warning Signs After Dilation and Curettage (D&C) [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025