Frequency of IV Cannula Replacement

Evidence-Based Recommendations for Different Types of IV Cannulas

The Centers for Disease Control and Prevention recommends that peripheral intravenous cannulas in adults should be replaced every 72-96 hours to prevent phlebitis and other complications 1, 2
For pediatric patients, peripheral catheters should not be routinely replaced but left in place until IV therapy is completed, unless complications occur 1, 3
Catheters inserted under emergency conditions should be replaced within 48 hours 1, 2
Central venous catheters should not be routinely replaced solely to reduce infection risk, but instead removed when no longer clinically necessary or when complications develop 1, 2, 3
Arterial catheters should be removed as soon as they are no longer needed 4

Standard IV tubing and add-on devices should be replaced no more frequently than every 72-96 hours 1, 4
Tubing used for blood, blood products, or lipid emulsions should be replaced within 24 hours of initiating the infusion 1, 2, 4
Tubing for propofol infusions requires more frequent changes - every 6 or 12 hours according to manufacturer recommendations 1, 2
Needleless components should be changed at least as frequently as the administration set (every 72-96 hours) 4
Injection ports should be cleaned with 70% alcohol or an iodophor before accessing the system 1, 2

Always inspect the IV site daily for signs of complications 3
When showering, protect the catheter and connecting device with an impermeable cover to prevent introducing organisms into the catheter 1, 2
Designate trained personnel for insertion and maintenance of intravascular catheters to minimize complications 1, 5