Diagnosis of Bronchopneumonia
Clinical Presentation
- The American Thoracic Society recommends that bronchopneumonia diagnosis should be suspected when patients present with new respiratory symptoms, such as cough, sputum production, dyspnea, especially when accompanied by fever 1
- The American College of Chest Physicians suggests that abnormal auscultatory findings, including crackles and abnormal breath sounds on chest examination, are indicative of bronchopneumonia 1
- Atypical presentations in elderly patients, such as confusion, failure to thrive, worsening chronic illness, or falls, often without fever but with tachypnea present, should raise suspicion for bronchopneumonia 1
Essential Diagnostic Studies
- The American College of Radiology recommends that standard posteroanterior and lateral chest radiographs are essential and should be obtained in all patients with suspected pneumonia 1
- Chest radiography can differentiate pneumonia from mimicking conditions and identify coexisting problems, such as bronchial obstruction, pleural effusion, or multilobar involvement 1
Microbiological Testing
- The Infectious Diseases Society of America suggests that sputum Gram stain and culture should be obtained before antibiotics when a good quality specimen is available 2
- Blood cultures, with two sets, should be obtained in hospitalized patients, as they have high specificity when positive, though sensitivity is less than 25% 3, 4
- Pleural fluid analysis should be performed if an effusion is present, with testing for Gram stain, culture, cell count, protein, LDH, glucose, and pH 3
Special Pathogen Testing
- The American Thoracic Society recommends that Legionella urinary antigen testing should be performed if severe pneumonia or treatment failure is suspected 2, 5
- Cultures for tuberculosis and endemic fungi should be obtained in at-risk patients with an appropriate epidemiologic history 2
Advanced Diagnostic Procedures
- The American College of Chest Physicians suggests that bronchoscopy is usually not needed and patience is necessary to observe full radiographic clearing 6, 7, 8
- Bronchoscopy should be considered when a patient is less than 55 years old, a nonsmoker, with multilobar disease and persistent infiltrates, or when there is no clinical response within 72 hours of appropriate therapy 7, 5
Diagnostic Limitations
- The American Thoracic Society notes that even with extensive testing, a specific etiology cannot be identified in up to half or more of all community-acquired pneumonia cases 1