Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/30/2025

Changes in SHBG Levels After Varicocele Surgery in Men

Monitoring Recommendations

  • When measuring SHBG levels pre- and post-surgery, it's essential to use the same assay to ensure accurate comparison, as recommended by Endocrine Reviews 1
  • For proper interpretation of trends, measurements should be performed with the same assay in the same laboratory with assay-specific reference values, according to Endocrine Reviews 1