Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 11/5/2025

Maximum Recommended Dose of Famotidine for Specific Indications

Standard Maximum Dosing by Indication

  • The Society of Critical Care Medicine recommends a maximum dose of 40 mg daily for stress ulcer prophylaxis 1

Special Clinical Contexts

Critical Care and Premedication Protocols

  • The American College of Cardiology and Journal for ImmunoTherapy of Cancer suggest that the standard dose for premedication protocols is 20 mg IV or PO 2, 3

Pediatric Dosing

  • The American Academy of Pediatrics recommends a maximum dose of 1 mg/kg/day divided in 2 doses for children <40 kg 4

REFERENCES

1

Combination Therapy with Omeprazole and Famotidine [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

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