Stopping Methylphenidate Extended Release

Monitoring and Management

• The American Academy of Pediatrics recommends observing behavioral changes, concentration problems, and hyperactivity that can return after stopping methylphenidate, and using standardized assessment scales to monitor symptom return 2
• The American Academy of Pediatrics suggests considering behavioral therapy as a non-pharmacological treatment after stopping methylphenidate, especially in children, and providing extra monitoring for adolescents with a history of substance use 2
• The National Comprehensive Cancer Network recommends evaluating the underlying condition before stopping methylphenidate in patients using it for indications other than ADHD, such as cancer-related fatigue or opioid-induced sedation 3, 4
• The American Academy of Pediatrics recommends scheduling psychiatric follow-up for patients with comorbid mood or anxiety disorders before stopping methylphenidate 2
• The American Academy of Pediatrics suggests using standardized assessment scales from parents/teachers or self-report to monitor symptom return after stopping methylphenidate 1