Pressure Limit in Volume Support Mode
Understanding Volume Support Mode
- The American Thoracic Society recommends maintaining a plateau pressure ≤30 cmH₂O in volume support mode, with the ventilator automatically adjusting pressure support breath-by-breath to deliver the preset tidal volume while respecting this pressure ceiling 1, 2
Recommended Pressure Limits
- The American College of Chest Physicians recommends setting the plateau pressure ceiling at ≤30 cmH₂O for patients with ARDS and acute respiratory failure, which represents the most widely validated pressure threshold associated with reduced mortality and ventilator-induced lung injury 1, 3, 4
- For patients with normal lungs, consider a slightly lower threshold of ≤28 cmH₂O 2
- In cases of increased chest wall elastance, plateau pressures up to 29-32 cmH₂O may be acceptable since the elevated pressure reflects chest wall stiffness rather than excessive lung stretch 2, 5
Target Tidal Volume Settings
- Set target tidal volume at 6 mL/kg predicted body weight as the starting point, with the ventilator adjusting pressure support to achieve this volume while respecting the pressure limit 1, 3, 4
- Calculate predicted body weight using the formula: Male = 50 + 2.3 [height (inches) - 60]; Female = 45.5 + 2.3 [height (inches) - 60] [3, 4]
- If plateau pressure exceeds 30 cmH₂O despite 6 mL/kg, reduce tidal volume target progressively down to 4 mL/kg predicted body weight 1, 3, 5
Maximum Pressure Support Settings
- The American Academy of Sleep Medicine recommends that the maximum pressure support should not exceed 20 cmH₂O 6
- For patients ≥12 years, maximum IPAP should be ≤30 cmH₂O; for patients <12 years, limit IPAP to ≤20 cmH₂O 6
Critical Monitoring Parameters
- Monitor plateau pressure to ensure it remains ≤30 cmH₂O 1, 2
- Monitor driving pressure (plateau pressure minus PEEP) and intervene if values >15 cmH₂O are predicted to worsen outcomes 5
Adjusting for Patient Effort and Asynchrony
- Increase pressure support by 1-2 cmH₂O increments every 5 minutes if tidal volume remains inadequate, but never exceed the 30 cmH₂O plateau pressure ceiling 6, 2
- Patient effort generates higher transalveolar pressures for a given plateau pressure, so actively breathing patients may require more conservative pressure limits 1