Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/28/2025

Effects of Appendectomy on Health

Introduction to Appendectomy

  • The appendix is not essential for survival, and millions of people live healthy lives after appendectomy, as stated by the World Journal of Emergency Surgery guidelines 1, 2

Clinical Context and Management

  • Appendectomy remains mandatory for complicated (perforating) appendicitis, failed non-operative management of uncomplicated appendicitis, and appendicoliths with high failure rates of conservative management, according to the World Journal of Emergency Surgery 2, 3
  • Non-operative management with antibiotics is now recommended for selected patients with uncomplicated appendicitis without appendicolith, avoiding appendectomy in 62-81% of cases, as per the World Journal of Emergency Surgery guidelines 2, 3