Antibiotic Treatment for Prostatitis

Recommended Antibiotics

• The World Health Organization recommends ciprofloxacin as the first-choice antibiotic for mild-to-moderate prostatitis, if local resistance patterns allow its use 1, 2, 3
• For severe prostatitis, the World Health Organization recommends ceftriaxone or cefotaxime as first-choice options, with amikacin as second-choice 1, 2, 3

Antibiotics to Avoid

• The American Urological Association recommends avoiding amoxicillin or ampicillin empirically due to very high worldwide resistance rates 4