Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/2/2025

Treatment for Moderately Advanced Degenerative Disk Disease at T12-L1 with Circumferential Disk Bulging

Initial Conservative Management

  • Physical therapy focusing on core strengthening and flexibility exercises should be the cornerstone of initial treatment for degenerative disk disease at the thoracolumbar junction, according to the American Association of Neurological Surgeons 1

When to Consider Surgical Intervention

  • Intractable pain that is refractory to at least 6 months of comprehensive conservative management is an indication for surgical intervention, as recommended by the Journal of Neurosurgery 2, 3

Surgical Options

  • Decompression without fusion is typically sufficient for patients with primarily radicular symptoms without significant axial back pain, as stated by the Journal of Neurosurgery 4, 5, 6
  • The American Association of Neurological Surgeons does not recommend routine fusion following primary disc excision for isolated herniated discs causing radiculopathy 1

Important Considerations and Caveats

  • Meta-analyses comparing surgical procedures (decompression, spinal fusion) versus non-surgical treatment for degenerative spine conditions have shown similar outcomes between operative and non-operative interventions, highlighting the importance of appropriate patient selection, according to the BMJ 7