Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/22/2025

Croup Diagnosis and Management

Etiology

  • Parainfluenza viruses (types 1-3) are the most common causative agents of croup, with types 1 and 2 most commonly causing croup syndrome in children 1
  • Other viruses, including respiratory syncytial virus, influenza, adenovirus, and human metapneumovirus, can also cause croup 1

Critical Differential Diagnoses to Exclude

  • Pertussis should be considered in the differential diagnosis of croup, characterized by a cough lasting ≥2 weeks with paroxysms, post-tussive vomiting, and inspiratory whooping sound 2