Cephalexin Use in Pregnancy for UTI

Introduction to Cephalexin Therapy

• The American Academy of Pediatrics suggests being aware of local susceptibility patterns for E. coli to cephalexin, as geographic variability exists 1, 2, 3

Safety and Efficacy Considerations

• Cephalexin should not be used as monotherapy for acute pyelonephritis in pregnancy, as oral cephalosporins achieve lower blood concentrations than parenteral agents, according to the European Association of Urology 4