Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/20/2025

Metoclopramide Dosing Considerations

Patient Factors

  • More severe side effects, such as behavioral changes, delirium, and hallucinations, have been associated with high plasma drug concentrations, particularly in patients with renal insufficiency 1
  • Elderly patients often have decreased renal function and may require additional dose considerations beyond those based solely on creatinine clearance 2