Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/13/2025

Assessment and Treatment of Depression and Anxiety in Young Adults

Symptom Severity and Treatment Guidance

  • The PHQ-9 score of 20 indicates moderate to severe depression requiring pharmacological intervention, as suggested by the American College of Physicians, with a moderate level of evidence 1, 2
  • The GAD-7 score of 21 indicates severe anxiety, with scores ≥15 considered severe, according to the American Psychiatric Association, with a high level of evidence 1, 3
  • Reassessing symptoms using PHQ-9 and GAD-7 at each visit is crucial to track progress, as recommended by the American Academy of Family Physicians, with a strong level of evidence 1, 2
  • Consider referral to a psychiatrist if there is inadequate response after dose optimization or if side effects are problematic, as suggested by the American Medical Association, with a moderate level of evidence 3, 4