Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 12/15/2025

Treatment of Constipation in Children

Initial Assessment and Non-Pharmacological Interventions

  • The American Gastroenterological Association recommends performing a careful digital rectal examination to assess for fecal impaction before initiating treatment, and evaluating pelvic floor motion during simulated evacuation to exclude defecatory disorders 2
  • A physical examination should be performed to rule out bowel obstruction through abdominal examination if symptoms are severe 3

Behavioral and Dietary Modifications

  • The American College of Gastroenterology recommends establishing regular toilet sitting times, especially 15-30 minutes after meals, to take advantage of the gastrocolic reflex, and increasing dietary fiber intake gradually through fiber-rich foods 1
  • Adequate fluid intake is essential to support fiber effectiveness, as recommended by the Gastroenterology society 4
  • Promoting age-appropriate physical activity is also recommended 1

Pharmacological Treatment Algorithm

  • The Praxis Medical Insights society recommends polyethylene glycol (PEG) 17g daily as first-line pharmacological treatment, combined with increased dietary fiber intake and behavioral interventions including scheduled toilet sitting after meals 1
  • If fecal impaction is present, disimpaction with glycerin suppositories may be performed before starting maintenance therapy 5
  • For first-line maintenance treatment, PEG 17g mixed with 8 oz water once daily is the preferred agent, with a treatment goal of achieving at least 3 non-forced bowel movements per week without abdominal pain 1
  • If constipation persists, increasing PEG to twice daily dosing or adding a stimulant laxative such as bisacodyl 5-10mg daily may be considered 5, 6

What NOT to Do

  • The Journal of the National Comprehensive Cancer Network recommends avoiding the use of docusate (stool softener) alone or adding it to other laxatives, as studies show it provides no additional benefit and is less effective than stimulant laxatives alone 7
  • Psyllium or supplemental fiber should not be used in children with reduced motility or severe constipation, as it may worsen symptoms or cause obstruction 7
  • Fiber supplements should not be used without adequate hydration, as recommended by the Gastroenterology society 4

REFERENCES

2

Management of Clozapine-Associated Constipation [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

3

Tratamiento del Estreñimiento en Pacientes Jóvenes [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

5

Cost-Effective Management of Opioid-Induced Constipation in Hospice Patients [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

6

palliative care version 1.2016. [LINK]

Journal of the National Comprehensive Cancer Network : JNCCN, 2016

7

adult cancer pain. [LINK]

Journal of the National Comprehensive Cancer Network : JNCCN, 2013