Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/12/2025

Median Survival of Untreated Acute Leukemia

Comparative Survival Data Supporting Treatment Necessity

  • Even with best supportive care alone (without chemotherapy), median survival was only 3.6 months in patients aged ≥61 years, according to the National Comprehensive Cancer Network 1
  • The use of low-intensity approaches or supportive care with hypomethylating agents can extend survival significantly beyond the natural history of the disease in elderly or frail patients, as recommended by the National Comprehensive Cancer Network 1

REFERENCES

1

acute myeloid leukemia, version 3.2019, nccn clinical practice guidelines in oncology. [LINK]

Journal of the National Comprehensive Cancer Network : JNCCN, 2019