Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 6/16/2025

Medication Management Guidelines

Introduction to Medication Dosing

  • The dose of medications like lisdexamfetamine should be increased gradually, with a weekly increase of 10 milligrams, as recommended by the American College of Obstetricians and Gynecologists 1

Dosing and Titration

  • The dose of lisdexamfetamine should be adjusted with a 10 milligram weekly increase, as recommended by guideline societies 1
  • Before each dose increase, clinical response and patient tolerance should be evaluated, as part of proper medical practice 1

Monitoring and Safety

  • The maximum recommended dose is 70 milligrams once daily, according to the American College of Obstetricians and Gynecologists 1
  • Vital signs such as blood pressure and heart rate should be monitored regularly, as recommended by the American Academy of Child and Adolescent Psychiatry 2
  • Patient weight should be measured at each visit to assess potential side effects like decreased appetite and weight loss, as recommended by the American Academy of Child and Adolescent Psychiatry 2
  • Systematic evaluation of side effects should be performed by asking specific questions about known side effects such as insomnia, anorexia, headache, and mood changes, as recommended by the American Academy of Child and Adolescent Psychiatry 2

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