Obsolescence of Concomitant Non‑Bismuth Quadruple Therapy for Helicobacter pylori Eradication
Guideline Reclassification
Rationale for Obsolescence
Recommended First‑Line Regimens
Bismuth Quadruple Therapy (14 days) – Preferred First‑Line
Rifabutin Triple Therapy (14 days) – Alternative First‑Line
PPI Selection and Potency
| PPI | Equivalent Omeprazole Dose | |-----|----------------------------| | Rabeprazole 20 mg | 36 mg omeprazole | | Esomeprazole 20 mg | 32 mg omeprazole | | (Pantoprazole 40 mg ≈ 9 mg omeprazole – avoid) | — |