Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/3/2025

Heart Failure Cardiomyopathy Treatment Guidelines

Current Recommendations

  • The European Society of Cardiology and American College of Cardiology/American Heart Association recommend against the use of imatinib for heart failure cardiomyopathy treatment, as it is not included in their guidelines 1, 2
  • The European Society of Cardiology and American College of Cardiology/American Heart Association guidelines recommend standard guideline-directed medical therapy for heart failure, including ACE inhibitors, ARBs, or ARNI, beta-blockers, mineralocorticoid receptor antagonists, and SGLT2 inhibitors 1, 2
  • The American College of Cardiology/American Heart Association guidelines specifically recommend the use of SGLT2 inhibitors for heart failure treatment 2
  • The European Society of Cardiology guidelines recommend diuretics for symptom relief in heart failure patients 1
  • The European Society of Cardiology recommends optimizing evidence-based therapies rather than introducing experimental agents for patients with worsening heart failure 1